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| Management number | 204569870 | Release Date | 2025/10/14 | List Price | $25.58 | Model Number | 204569870 | ||
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Simparica Trio for Dogs 88.1-132.0 lbs is a once-monthly, liver-flavored chewable providing three-in-one defense against fleas, ticks, and heartworm disease while treating roundworms and hookworms. Its fast-acting sarolaner, moxidectin, and pyrantel pamoate combination delivers broad-spectrum parasite control and convenient dosing in a single tasty tablet.
Sarolaner 56 mg, Moxidectin 1.12 mg, Pyrantel Pamoate 200 mg
Beef liver flavor, microcrystalline cellulose, silicon dioxide, magnesium stearate, other excipients
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Variants |
Active Ingredients |
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|
Weight Range |
Box Label Color |
Sarolaner (mg) |
Moxidectin (mg) |
Pyrantel (mg) |
|
2.8-5.5 lbs |
Yellow |
5 mg |
0.1 mg |
20 mg |
|
5.6-11 lbs |
Purple |
10 mg |
0.2 mg |
50 mg |
|
11.1-22 lbs |
Orange |
20 mg |
0.4 mg |
100 mg |
|
22.1-44 lbs |
Blue |
40 mg |
0.8 mg |
200 mg |
|
44.1-88 lbs |
Green |
48 mg |
0.96 mg |
200 mg |
|
88.1-132 lbs |
Brown |
56 mg |
1.12 mg |
200 mg |
We offer ground, express, priority, and international delivery; see our shipping policy for details.
For return instructions or product concerns, please refer to our detailed refund policy.
Prescription items are NON-RETURNABLE and NON-REFUNDABLE.
Ans: Simparica Trio kills adult fleas within 4 hours and five tick species within 8 hours following oral administration in dogs weighing 88.1-132.0 lbs. This rapid action helps stop parasite feeding and reduces the risk of vector-borne disease transmission effectively.
Ans: Yes, Simparica Trio can be safely administered alongside veterinarian-prescribed heartworm, tick, or mite preventives, vaccines, and antibiotics. Always inform your veterinarian of all current medications to avoid potential interactions or overlapping therapies.
Ans: If a monthly dose is missed, administer Simparica Trio as soon as you remember and then resume the regular dosing schedule. Do not give two tablets on the same day to make up for the missed dose to minimize the risk of adverse reactions.
Ans: Use caution when administering Simparica Trio to dogs with a history of seizures or neurological disorders. The isoxazoline ingredient sarolaner may induce neurologic signs in susceptible animals; consult your veterinarian before beginning treatment.
Ans: Yes, all dogs must test negative for heartworm infection before the first Simparica Trio dose. Treating an infected dog can cause severe reactions as the medication eliminates circulating microfilariae from the bloodstream.
If you notice any omissions or errors in the product information on this page, please use the correction request form below.
Correction Request Form